2025 NFL Season
NFL Week 16 picks & predictions
A pick for every game — the betting favorite with its implied win %, the pick against the spread, and how the PickemSZN crowd is leaning. See the full schedule & odds or the most popular picks.
Odds-favorite picks this week: 9–7 (56%)
PHI
10-5
29 – 18
Final
WSH
4-11
Odds pick
PHI 56% to win
Lean
Against the spread
PHI -1.5
Crowd pick
PHI 100%
Odds pick hit ✓
TB
7-8
20 – 23
Final
CAR
8-7
Odds pick
TB 61% to win
Lean
Against the spread
TB -3
Crowd pick
CAR 75%
Upset watch — crowd fading the favorite Odds pick missed ✗
ATL
6-9
26 – 19
Final
ARI
3-12
Odds pick
ATL 61% to win
Lean
Against the spread
ATL -3
Crowd pick
No picks yet
Odds pick hit ✓
CIN
5-10
45 – 21
Final
MIA
6-9
Odds pick
CIN 56% to win
Lean
Against the spread
CIN -1.5
Crowd pick
CIN 100%
Odds pick hit ✓
BUF
11-4
23 – 20
Final
CLE
3-12
Odds pick
BUF 87% to win
Strong
Against the spread
BUF -10.5
Crowd pick
BUF 75%
Odds pick hit ✓
MIN
7-8
16 – 13
Final
NYG
2-13
Odds pick
MIN 60% to win
Lean
Against the spread
MIN -2.5
Crowd pick
No picks yet
Odds pick hit ✓
NE
12-3
28 – 24
Final
BAL
7-8
Odds pick
BAL 81% to win
Strong
Against the spread
BAL -8.5
Crowd pick
No picks yet
Odds pick missed ✗
GB
9-5-1
16 – 22
Final
CHI
11-4
Odds pick
GB 57% to win
Lean
Against the spread
GB -2.5
Crowd pick
CHI 66.7%
Upset watch — crowd fading the favorite Odds pick missed ✗
SF
11-4
48 – 27
Final
IND
8-7
Odds pick
SF 72% to win
Solid
Against the spread
SF -5.5
Crowd pick
No picks yet
Odds pick hit ✓
LAR
11-4
37 – 38
Final
SEA
12-3
Odds pick
SEA 55% to win
Toss-up
Against the spread
SEA -1.5
Crowd pick
LAR 100%
Upset watch — crowd fading the favorite Odds pick hit ✓
PIT
9-6
29 – 24
Final
DET
8-7
Odds pick
DET 78% to win
Strong
Against the spread
DET -7
Crowd pick
DET 100%
Odds pick missed ✗
LAC
11-4
34 – 17
Final
DAL
6-8-1
Odds pick
DAL 55% to win
Toss-up
Against the spread
DAL -1.5
Crowd pick
No picks yet
Odds pick missed ✗
LV
2-13
21 – 23
Final
HOU
10-5
Odds pick
HOU 93% to win
Strong
Against the spread
HOU -14.5
Crowd pick
HOU 75%
Odds pick hit ✓
KC
6-9
9 – 26
Final
TEN
3-12
Odds pick
KC 62% to win
Lean
Against the spread
KC -3
Crowd pick
No picks yet
Odds pick missed ✗
JAX
11-4
34 – 20
Final
DEN
12-3
Odds pick
DEN 64% to win
Solid
Against the spread
DEN -3.5
Crowd pick
DEN 75%
Odds pick missed ✗
NYJ
3-12
6 – 29
Final
NO
5-10
Odds pick
NO 74% to win
Strong
Against the spread
NO -6.5
Crowd pick
NO 100%
Odds pick hit ✓
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