2025 NFL Season
NFL Week 1 picks & predictions
A pick for every game — the betting favorite with its implied win %, the pick against the spread, and how the PickemSZN crowd is leaning. See the full schedule & odds or the most popular picks.
Odds-favorite picks this week: 13–3 (81%)
KC
0-1
21 – 27
Final
LAC
1-0
Odds pick
KC 63% to win
Solid
Against the spread
KC -3
Crowd pick
KC 66.7%
Odds pick missed ✗
NYG
0-1
6 – 21
Final
WSH
1-0
Odds pick
WSH 74% to win
Strong
Against the spread
WSH -6.5
Crowd pick
WSH 100%
Odds pick hit ✓
DAL
0-1
20 – 24
Final
PHI
1-0
Odds pick
PHI 81% to win
Strong
Against the spread
PHI -8.5
Crowd pick
PHI 100%
Odds pick hit ✓
LV
1-0
20 – 13
Final
NE
0-1
Odds pick
NE 61% to win
Lean
Against the spread
NE -2.5
Crowd pick
NE 66.7%
Odds pick missed ✗
TEN
0-1
12 – 20
Final
DEN
1-0
Odds pick
DEN 83% to win
Strong
Against the spread
DEN -8.5
Crowd pick
DEN 100%
Odds pick hit ✓
TB
1-0
23 – 20
Final
ATL
0-1
Odds pick
TB 53% to win
Toss-up
Against the spread
TB -1.5
Crowd pick
TB 100%
Odds pick hit ✓
MIA
0-1
8 – 33
Final
IND
1-0
Odds pick
IND 53% to win
Toss-up
Against the spread
IND -1.5
Crowd pick
MIA 66.7%
Upset watch — crowd fading the favorite Odds pick hit ✓
PIT
1-0
34 – 32
Final
NYJ
0-1
Odds pick
PIT 61% to win
Lean
Against the spread
PIT -3
Crowd pick
PIT 100%
Odds pick hit ✓
CIN
1-0
17 – 16
Final
CLE
0-1
Odds pick
CIN 70% to win
Solid
Against the spread
CIN -5.5
Crowd pick
CIN 100%
Odds pick hit ✓
CAR
0-1
10 – 26
Final
JAX
1-0
Odds pick
JAX 67% to win
Solid
Against the spread
JAX -4.5
Crowd pick
JAX 66.7%
Odds pick hit ✓
ARI
1-0
20 – 13
Final
NO
0-1
Odds pick
ARI 73% to win
Strong
Against the spread
ARI -6
Crowd pick
ARI 66.7%
Odds pick hit ✓
BAL
0-1
40 – 41
Final
BUF
1-0
Odds pick
BAL 54% to win
Toss-up
Against the spread
BAL -1.5
Crowd pick
BUF 75%
Upset watch — crowd fading the favorite Odds pick missed ✗
HOU
0-1
9 – 14
Final
LAR
1-0
Odds pick
LAR 63% to win
Solid
Against the spread
LAR -3
Crowd pick
LAR 75%
Odds pick hit ✓
MIN
1-0
27 – 24
Final
CHI
0-1
Odds pick
MIN 54% to win
Toss-up
Against the spread
MIN -1.5
Crowd pick
MIN 75%
Odds pick hit ✓
SF
1-0
17 – 13
Final
SEA
0-1
Odds pick
SF 57% to win
Lean
Against the spread
SF -1.5
Crowd pick
SEA 100%
Upset watch — crowd fading the favorite Odds pick hit ✓
DET
0-1
13 – 27
Final
GB
1-0
Odds pick
GB 54% to win
Toss-up
Against the spread
GB -1.5
Crowd pick
No picks yet
Odds pick hit ✓
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