Week 1 · 2025 NFL Season
Arizona Cardinals vs New Orleans Saints
Sun, Sep 7, 2025, 1:00 PM EDT · CBS
Caesars Superdome, New Orleans
Final — Arizona Cardinals win
Arizona Cardinals visit the New Orleans Saints at Caesars Superdome in Week 1 of the 2025 NFL season. Final: Arizona Cardinals 20, New Orleans Saints 13.
Betting lines
Moneyline
Arizona Cardinals: 1.37
New Orleans Saints: 3.20
Spread
Arizona Cardinals: -6
New Orleans Saints: +6
Over / Under
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Odds are decimal (from Betfair) and reflect the market as of the last update. How to read these →
Injury report
Arizona Cardinals
- Kaleb Proctor (DT) — Questionable
- Tip Reiman (TE) — Questionable
- Karson Sharar (LB) — Questionable
- Walter Nolen III (DT) — Questionable
- Garrett Williams (CB) — Questionable
New Orleans Saints
- Devin Neal (RB) — Questionable
- Jordyn Tyson (WR) — Questionable
- Kendre Miller (RB) — Questionable
- Christen Miller (DT) — Questionable
- Nick Saldiveri (OT) — Out
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