2021 NFL Season
NFL Week 5 picks & predictions
A pick for every game — the betting favorite with its implied win %, the pick against the spread, and how the PickemSZN crowd is leaning. See the full schedule & odds or the most popular picks.
Odds-favorite picks this week: 13–3 (81%)
GB
4-1
25 – 22
Final
CIN
3-2
Odds pick
GB 61% to win
Lean
Against the spread
Pick'em / no spread
Crowd pick
GB 100%
Odds pick hit ✓
DET
0-5
17 – 19
Final
MIN
2-3
Odds pick
MIN 77% to win
Strong
Against the spread
Pick'em / no spread
Crowd pick
MIN 100%
Odds pick hit ✓
CLE
3-2
42 – 47
Final
LAC
4-1
Odds pick
LAC 54% to win
Toss-up
Against the spread
Pick'em / no spread
Crowd pick
LAC 100%
Odds pick hit ✓
MIA
1-4
17 – 45
Final
TB
4-1
Odds pick
TB 80% to win
Strong
Against the spread
Pick'em / no spread
Crowd pick
TB 100%
Odds pick hit ✓
SF
2-3
10 – 17
Final
ARI
5-0
Odds pick
ARI 69% to win
Solid
Against the spread
Pick'em / no spread
Crowd pick
ARI 100%
Odds pick hit ✓
DEN
3-2
19 – 27
Final
PIT
2-3
Odds pick
PIT 52% to win
Toss-up
Against the spread
Pick'em / no spread
Crowd pick
No picks yet
Odds pick hit ✓
BUF
4-1
38 – 20
Final
KC
2-3
Odds pick
KC 57% to win
Lean
Against the spread
Pick'em / no spread
Crowd pick
KC 100%
Odds pick missed ✗
NYG
1-4
20 – 44
Final
DAL
4-1
Odds pick
DAL 75% to win
Strong
Against the spread
Pick'em / no spread
Crowd pick
DAL 100%
Odds pick hit ✓
NO
3-2
33 – 22
Final
WSH
2-3
Odds pick
NO 56% to win
Lean
Against the spread
Pick'em / no spread
Crowd pick
No picks yet
Odds pick hit ✓
IND
1-4
25 – 31
Final
BAL
4-1
Odds pick
BAL 75% to win
Strong
Against the spread
Pick'em / no spread
Crowd pick
No picks yet
Odds pick hit ✓
CHI
3-2
20 – 9
Final
LV
3-2
Odds pick
LV 67% to win
Solid
Against the spread
Pick'em / no spread
Crowd pick
LV 100%
Odds pick missed ✗
TEN
3-2
37 – 19
Final
JAX
0-5
Odds pick
TEN 66% to win
Solid
Against the spread
Pick'em / no spread
Crowd pick
TEN 100%
Odds pick hit ✓
PHI
2-3
21 – 18
Final
CAR
3-2
Odds pick
CAR 63% to win
Solid
Against the spread
Pick'em / no spread
Crowd pick
CAR 100%
Odds pick missed ✗
NYJ
1-4
20 – 27
Final
ATL
2-3
Odds pick
ATL 61% to win
Lean
Against the spread
Pick'em / no spread
Crowd pick
ATL 100%
Odds pick hit ✓
LAR
4-1
26 – 17
Final
SEA
2-3
Odds pick
LAR 56% to win
Lean
Against the spread
Pick'em / no spread
Crowd pick
SEA 100%
Upset watch — crowd fading the favorite Odds pick hit ✓
NE
2-3
25 – 22
Final
HOU
1-4
Odds pick
NE 79% to win
Strong
Against the spread
Pick'em / no spread
Crowd pick
No picks yet
Odds pick hit ✓
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