2021 NFL Season
NFL Week 4 picks & predictions
A pick for every game — the betting favorite with its implied win %, the pick against the spread, and how the PickemSZN crowd is leaning. See the full schedule & odds or the most popular picks.
Odds-favorite picks this week: 10–6 (63%)
HOU
1-3
0 – 40
Final
BUF
3-1

Odds pick
BUF 91% to win
Strong
Against the spread
Pick'em / no spread
Crowd pick
BUF 100%
Odds pick hit ✓
NYG
1-3
27 – 21
Final
NO
2-2

Odds pick
NO 78% to win
Strong
Against the spread
Pick'em / no spread
Crowd pick
NO 100%
Odds pick missed ✗
ARI
4-0
37 – 20
Final
LAR
3-1

Odds pick
LAR 69% to win
Solid
Against the spread
Pick'em / no spread
Crowd pick
No picks yet
Odds pick missed ✗
LV
3-1
14 – 28
Final
LAC
3-1

Odds pick
LAC 63% to win
Solid
Against the spread
Pick'em / no spread
Crowd pick
LV 100%
Upset watch — crowd fading the favorite Odds pick hit ✓
WSH
2-2
34 – 30
Final
ATL
1-3

Odds pick
WSH 54% to win
Toss-up
Against the spread
Pick'em / no spread
Crowd pick
ATL 100%
Upset watch — crowd fading the favorite Odds pick hit ✓
JAX
0-4
21 – 24
Final
CIN
3-1

Odds pick
CIN 75% to win
Strong
Against the spread
Pick'em / no spread
Crowd pick
CIN 100%
Odds pick hit ✓
IND
1-3
27 – 17
Final
MIA
1-3

Odds pick
MIA 56% to win
Lean
Against the spread
Pick'em / no spread
Crowd pick
No picks yet
Odds pick missed ✗
TEN
2-2
24 – 27
Final
NYJ
1-3

Odds pick
TEN 79% to win
Strong
Against the spread
Pick'em / no spread
Crowd pick
TEN 100%
Odds pick missed ✗
BAL
3-1
23 – 7
Final
DEN
3-1

Odds pick
DEN 51% to win
Toss-up
Against the spread
Pick'em / no spread
Crowd pick
DEN 100%
Odds pick missed ✗
TB
3-1
19 – 17
Final
NE
1-3

Odds pick
TB 73% to win
Strong
Against the spread
Pick'em / no spread
Crowd pick
No picks yet
Odds pick hit ✓
CAR
3-1
28 – 36
Final
DAL
3-1

Odds pick
DAL 67% to win
Solid
Against the spread
Pick'em / no spread
Crowd pick
CAR 100%
Upset watch — crowd fading the favorite Odds pick hit ✓
CLE
3-1
14 – 7
Final
MIN
1-3

Odds pick
CLE 56% to win
Lean
Against the spread
Pick'em / no spread
Crowd pick
MIN 100%
Upset watch — crowd fading the favorite Odds pick hit ✓
DET
0-4
14 – 24
Final
CHI
2-2

Odds pick
CHI 58% to win
Lean
Against the spread
Pick'em / no spread
Crowd pick
DET 100%
Upset watch — crowd fading the favorite Odds pick hit ✓
KC
2-2
42 – 30
Final
PHI
1-3

Odds pick
KC 76% to win
Strong
Against the spread
Pick'em / no spread
Crowd pick
KC 100%
Odds pick hit ✓
SEA
2-2
28 – 21
Final
SF
2-2

Odds pick
SF 60% to win
Lean
Against the spread
Pick'em / no spread
Crowd pick
No picks yet
Odds pick missed ✗
PIT
1-3
17 – 27
Final
GB
3-1

Odds pick
GB 74% to win
Strong
Against the spread
Pick'em / no spread
Crowd pick
GB 100%
Odds pick hit ✓
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