Week 4 · 2021 NFL Season
Seattle Seahawks vs San Francisco 49ers
Sun, Oct 3, 2021, 4:05 PM EDT
Final — Seattle Seahawks win
| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| SEA | 0 | 7 | 14 | 7 | 28 |
| SF | 7 | 0 | 6 | 8 | 21 |
Seattle Seahawks visit the San Francisco 49ers in Week 4 of the 2021 NFL season. Final: Seattle Seahawks 28, San Francisco 49ers 21.
Prediction & pick
Odds pick
San Francisco 49ers
60% implied ·Lean
Against the spread
Pick'em / no spread
Crowd pick
No picks yet
Odds pick missed ✗
The odds pick is simply the betting-line favorite; the crowd pick is how PickemSZN users are picking — not a proprietary model. See all Week 4 picks & predictions →
Betting lines
Moneyline
Seattle Seahawks: 2.34
San Francisco 49ers: 1.68
Spread
Seattle Seahawks: —
San Francisco 49ers: —
Over / Under
—
Odds are decimal (from Betfair) and reflect the market as of the last update. How to read these →
Team stats
SEA SF
14 1st Downs 23
234 Total Yards 457
129 Passing 314
105 Rushing 143
2-10 3rd down efficiency 2-14
5-27 Penalties 8-78
0 Turnovers 2
28:19 Possession 31:41
Leaders
SEA
- Passing YardsRussell Wilson (QB) — 16/23, 149 YDS, 2 TD
- Rushing YardsAlex Collins (RB) — 10 CAR, 44 YDS, 1 TD
- Receiving YardsDK Metcalf (WR) — 4 REC, 65 YDS, 1 TD
SF
- Passing YardsJimmy Garoppolo (QB) — 14/23, 165 YDS, 1 TD, 1 INT
- Rushing YardsTrey Sermon (RB) — 19 CAR, 89 YDS
- Receiving YardsDeebo Samuel (WR) — 8 REC, 156 YDS, 2 TD
Scoring summary
- Q1 9:35 SF Ross Dwelley 21 Yd pass from Jimmy Garoppolo (Mitch Wishnowsky Kick) 0–7
- Q2 1:54 SEA DK Metcalf 12 Yd pass from Russell Wilson (Jason Myers Kick) 7–7
- Q3 5:22 SEA Russell Wilson 16 Yd Run (Jason Myers Kick) 14–7
- Q3 4:26 SEA Freddie Swain 13 Yd pass from Russell Wilson (Jason Myers Kick) 21–7
- Q3 2:10 SF Deebo Samuel 76 Yd pass from Trey Lance (Mitch Wishnowsky PAT failed) 21–13
- Q4 12:07 SEA Alex Collins 14 Yd Run (Jason Myers Kick) 28–13
- Q4 1:20 SF Deebo Samuel 8 Yd pass from Trey Lance (Trey Lance Run for Two-Point Conversion) 28–21
Standings
2025 NFC West Standings
| Team | W-L | PF | PA |
|---|---|---|---|
| Seattle | 14-3 | 483 | 292 |
| Los Angeles | 12-5 | 518 | 346 |
| San Francisco | 12-5 | 437 | 371 |
| Arizona | 3-14 | 355 | 488 |
Referee Carl Cheffers
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