2021 NFL Season
NFL Week 6 picks & predictions
A pick for every game — the betting favorite with its implied win %, the pick against the spread, and how the PickemSZN crowd is leaning. See the full schedule & odds or the most popular picks.
Odds-favorite picks this week: 10–4 (71%)
CIN
4-2
34 – 11
Final
DET
0-6
Odds pick
CIN 63% to win
Solid
Against the spread
Pick'em / no spread
Crowd pick
No picks yet
Odds pick hit ✓
KC
3-3
31 – 13
Final
WSH
2-4
Odds pick
KC 76% to win
Strong
Against the spread
Pick'em / no spread
Crowd pick
KC 100%
Odds pick hit ✓
DAL
5-1
35 – 29
Final
NE
2-4
Odds pick
DAL 66% to win
Solid
Against the spread
Pick'em / no spread
Crowd pick
DAL 100%
Odds pick hit ✓
LV
4-2
34 – 24
Final
DEN
3-3
Odds pick
DEN 64% to win
Solid
Against the spread
Pick'em / no spread
Crowd pick
LV 100%
Upset watch — crowd fading the favorite Odds pick missed ✗
BUF
4-2
31 – 34
Final
TEN
4-2
Odds pick
BUF 72% to win
Solid
Against the spread
Pick'em / no spread
Crowd pick
BUF 100%
Odds pick missed ✗
GB
5-1
24 – 14
Final
CHI
3-3
Odds pick
GB 66% to win
Solid
Against the spread
Pick'em / no spread
Crowd pick
GB 100%
Odds pick hit ✓
SEA
2-4
20 – 23
Final
PIT
3-3
Odds pick
PIT 68% to win
Solid
Against the spread
Pick'em / no spread
Crowd pick
PIT 100%
Odds pick hit ✓
HOU
1-5
3 – 31
Final
IND
2-4
Odds pick
IND 81% to win
Strong
Against the spread
Pick'em / no spread
Crowd pick
IND 100%
Odds pick hit ✓
LAR
5-1
38 – 11
Final
NYG
1-5
Odds pick
LAR 92% to win
Strong
Against the spread
Pick'em / no spread
Crowd pick
LAR 100%
Odds pick hit ✓
MIN
3-3
34 – 28
Final
CAR
3-3
Odds pick
MIN 52% to win
Toss-up
Against the spread
Pick'em / no spread
Crowd pick
No picks yet
Odds pick hit ✓
TB
5-1
28 – 22
Final
PHI
2-4
Odds pick
TB 73% to win
Strong
Against the spread
Pick'em / no spread
Crowd pick
No picks yet
Odds pick hit ✓
MIA
1-5
20 – 23
Final
JAX
1-5
Odds pick
MIA 64% to win
Solid
Against the spread
Pick'em / no spread
Crowd pick
No picks yet
Odds pick missed ✗
ARI
6-0
37 – 14
Final
CLE
3-3
Odds pick
CLE 58% to win
Lean
Against the spread
Pick'em / no spread
Crowd pick
ARI 100%
Upset watch — crowd fading the favorite Odds pick missed ✗
LAC
4-2
6 – 34
Final
BAL
5-1
Odds pick
BAL 60% to win
Lean
Against the spread
Pick'em / no spread
Crowd pick
LAC 100%
Upset watch — crowd fading the favorite Odds pick hit ✓
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