Week 16 · 2021 NFL Season
San Francisco 49ers vs Tennessee Titans
Thu, Dec 23, 2021, 8:20 PM EST
Final — Tennessee Titans win
| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| SF | 7 | 3 | 0 | 7 | 17 |
| TEN | 0 | 0 | 10 | 10 | 20 |
San Francisco 49ers visit the Tennessee Titans in Week 16 of the 2021 NFL season. Final: San Francisco 49ers 17, Tennessee Titans 20.
Recap: Titans rally from 10 down at half, edge 49ers 20-17 →
Prediction & pick
Odds pick
San Francisco 49ers
62% implied ·Lean
Against the spread
Pick'em / no spread
Crowd pick
Tennessee Titans 100%
Odds pick missed ✗
The odds pick is simply the betting-line favorite; the crowd pick is how PickemSZN users are picking — not a proprietary model. See all Week 16 picks & predictions →
Betting lines
Moneyline
San Francisco 49ers: 1.62
Tennessee Titans: 2.58
Spread
San Francisco 49ers: —
Tennessee Titans: —
Over / Under
—
Odds are decimal (from Betfair) and reflect the market as of the last update. How to read these →
Team stats
SF TEN
22 1st Downs 16
389 Total Yards 278
306 Passing 188
83 Rushing 90
3-8 3rd down efficiency 9-16
5-41 Penalties 6-57
2 Turnovers 0
30:31 Possession 29:29
Leaders
SF
- Passing YardsJimmy Garoppolo (QB) — 26/35, 322 YDS, 1 TD, 2 INT
- Rushing YardsJeff Wilson Jr. (RB) — 14 CAR, 45 YDS, 1 TD
- Receiving YardsDeebo Samuel (WR) — 9 REC, 159 YDS
TEN
- Passing YardsRyan Tannehill (QB) — 22/29, 209 YDS, 1 TD
- Rushing YardsJeremy McNichols (RB) — 7 CAR, 31 YDS
- Receiving YardsA.J. Brown (WR) — 11 REC, 145 YDS, 1 TD
Scoring summary
- Q1 9:57 SF Jeff Wilson Jr. 1 Yd Run (Robbie Gould Kick) 7–0
- Q2 8:31 SF Robbie Gould 48 Yd Field Goal 10–0
- Q3 8:45 TEN Randy Bullock 38 Yd Field Goal 10–3
- Q3 7:13 TEN D'Onta Foreman 3 Yd Run (Randy Bullock Kick) 10–10
- Q4 13:02 TEN A.J. Brown 18 Yd pass from Ryan Tannehill (Randy Bullock Kick) 10–17
- Q4 2:20 SF Brandon Aiyuk 2 Yd pass from Jimmy Garoppolo (Robbie Gould Kick) 17–17
- Q4 0:04 TEN Randy Bullock 44 Yd Field Goal 17–20
Standings
2025 NFC West Standings
| Team | W-L | PF | PA |
|---|---|---|---|
| Seattle | 14-3 | 483 | 292 |
| Los Angeles | 12-5 | 518 | 346 |
| San Francisco | 12-5 | 437 | 371 |
| Arizona | 3-14 | 355 | 488 |
2025 AFC South Standings
| Team | W-L | PF | PA |
|---|---|---|---|
| Jacksonville | 13-4 | 474 | 336 |
| Houston | 12-5 | 404 | 295 |
| Indianapolis | 8-9 | 466 | 412 |
| Tennessee | 3-14 | 284 | 478 |
Referee Shawn Hochuli
Who's your pick?
Make your call on San Francisco 49ers vs Tennessee Titans and every other game, free, and see how you stack up on the leaderboard.
Make your picks