Week 1 · 2021 NFL Season
San Francisco 49ers vs Detroit Lions
Sun, Sep 12, 2021, 1:00 PM EDT
Final — San Francisco 49ers win
| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| SF | 7 | 24 | 7 | 3 | 41 |
| DET | 0 | 10 | 7 | 16 | 33 |
San Francisco 49ers visit the Detroit Lions in Week 1 of the 2021 NFL season. Final: San Francisco 49ers 41, Detroit Lions 33.
Recap: 49ers build 28-point lead, hold on for 41-33 win over Lions →
Prediction & pick
Odds pick
San Francisco 49ers
76% implied ·Strong
Against the spread
Pick'em / no spread
Crowd pick
San Francisco 49ers 100%
Odds pick hit ✓
The odds pick is simply the betting-line favorite; the crowd pick is how PickemSZN users are picking — not a proprietary model. See all Week 1 picks & predictions →
Betting lines
Moneyline
San Francisco 49ers: 1.31
Detroit Lions: 3.75
Spread
San Francisco 49ers: —
Detroit Lions: —
Over / Under
—
Odds are decimal (from Betfair) and reflect the market as of the last update. How to read these →
Team stats
SF DET
21 1st Downs 31
442 Total Yards 430
311 Passing 314
131 Rushing 116
3-9 3rd down efficiency 4-15
7-79 Penalties 5-45
2 Turnovers 1
26:33 Possession 33:27
Leaders
SF
- Passing YardsJimmy Garoppolo (QB) — 17/25, 314 YDS, 1 TD
- Rushing YardsElijah Mitchell (RB) — 19 CAR, 104 YDS, 1 TD
- Receiving YardsDeebo Samuel (WR) — 9 REC, 189 YDS, 1 TD
DET
- Passing YardsJared Goff (QB) — 38/57, 338 YDS, 3 TD, 1 INT
- Rushing YardsJamaal Williams (RB) — 9 CAR, 54 YDS, 1 TD
- Receiving YardsT.J. Hockenson (TE) — 8 REC, 97 YDS, 1 TD
Scoring summary
- Q1 5:41 SF Trent Sherfield 5 Yd pass from Trey Lance (Robbie Gould Kick) 7–0
- Q2 13:29 DET T.J. Hockenson 6 Yd pass from Jared Goff (Austin Seibert Kick) 7–7
- Q2 11:12 SF Elijah Mitchell 38 Yd Run (Robbie Gould Kick) 14–7
- Q2 6:13 DET Austin Seibert 49 Yd Field Goal 14–10
- Q2 2:25 SF JaMycal Hasty 3 Yd Run (Robbie Gould Kick) 21–10
- Q2 1:10 SF Dre Greenlaw 39 Yd Interception Return (Robbie Gould Kick) 28–10
- Q2 0:03 SF Robbie Gould 40 Yd Field Goal 31–10
- Q3 7:54 SF Deebo Samuel 79 Yd pass from Jimmy Garoppolo (Robbie Gould Kick) 38–10
- Q3 4:23 DET D'Andre Swift 43 Yd pass from Jared Goff (Austin Seibert Kick) 38–17
- Q4 9:53 SF Robbie Gould 52 Yd Field Goal 41–17
- Q4 1:53 DET Jamaal Williams 1 Yd Run (Jared Goff Pass to T.J. Hockenson for Two-Point Conversion) 41–25
- Q4 1:07 DET Quintez Cephus 2 Yd pass from Jared Goff (Jared Goff Pass to Quintez Cephus for Two-Point Conversion) 41–33
Standings
2025 NFC West Standings
| Team | W-L | PF | PA |
|---|---|---|---|
| Seattle | 14-3 | 483 | 292 |
| Los Angeles | 12-5 | 518 | 346 |
| San Francisco | 12-5 | 437 | 371 |
| Arizona | 3-14 | 355 | 488 |
2025 NFC North Standings
| Team | W-L | PF | PA |
|---|---|---|---|
| Chicago | 11-6 | 441 | 415 |
| Green Bay | 9-7-1 | 391 | 360 |
| Minnesota | 9-8 | 344 | 333 |
| Detroit | 9-8 | 481 | 413 |
Referee Brad Rogers
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