Week 3 · 2025 NFL Season
Indianapolis Colts vs Tennessee Titans
Sun, Sep 21, 2025, 1:00 PM EDT · CBS
Nissan Stadium, Nashville
Final — Indianapolis Colts win
Indianapolis Colts visit the Tennessee Titans at Nissan Stadium in Week 3 of the 2025 NFL season. Final: Indianapolis Colts 41, Tennessee Titans 20.
Betting lines
Moneyline
Indianapolis Colts: 2.05
Tennessee Titans: 1.80
Spread
Indianapolis Colts: +1.5
Tennessee Titans: -1.5
Over / Under
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Odds are decimal (from Betfair) and reflect the market as of the last update. How to read these →
Injury report
Indianapolis Colts
- Spencer Shrader (PK) — Questionable
- Daniel Jones (QB) — Questionable
- Alec Pierce (WR) — Questionable
- Charvarius Ward (CB) — Questionable
- Hunter Wohler (S) — Questionable
Tennessee Titans
- Jeffery Simmons (DT) — Questionable
- C.J. Ravenell (DE) — Injured Reserve
- Oluwafemi Oladejo (DE) — Questionable
- Marcus Harris (CB) — Questionable
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