Week 17 · 2025 NFL Season
Chicago Bears vs San Francisco 49ers
Sun, Dec 28, 2025, 8:20 PM EST · NBC
Levi's Stadium, Santa Clara
Final — San Francisco 49ers win
Chicago Bears visit the San Francisco 49ers at Levi's Stadium in Week 17 of the 2025 NFL season. Final: Chicago Bears 38, San Francisco 49ers 42.
Betting lines
Moneyline
Chicago Bears: 2.50
San Francisco 49ers: 1.56
Spread
Chicago Bears: +3.5
San Francisco 49ers: -3.5
Over / Under
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Odds are decimal (from Betfair) and reflect the market as of the last update. How to read these →
Injury report
Chicago Bears
- Dayo Odeyingbo (DE) — Questionable
- Kyler Gordon (CB) — Questionable
- Jedrick Wills Jr. (OT) — Questionable
- Ozzy Trapilo (OT) — Questionable
- Shemar Turner (DT) — Questionable
San Francisco 49ers
- Mac Jones (QB) — Questionable
- Brandon Aiyuk (WR) — Out
- George Kittle (TE) — Questionable
- Darrick Forrest (S) — Injured Reserve
- Nick Bosa (DE) — Questionable
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