Week 12 · 2021 NFL Season

Buffalo Bills vs New Orleans Saints

Thu, Nov 25, 2021, 8:20 PM EST

Buffalo Bills logo
Away · 7-4
31
New Orleans Saints logo
Home · 5-6
6

Final — Buffalo Bills win

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BUF7314731
NO00066

Buffalo Bills visit the New Orleans Saints in Week 12 of the 2021 NFL season. Final: Buffalo Bills 31, New Orleans Saints 6.

Recap: Allen throws for 4 TDs as Bills beat hobbled Saints, 31-6 →

Prediction & pick

Odds pick
Buffalo Bills
71% implied ·Solid
Against the spread
Pick'em / no spread
Crowd pick
Buffalo Bills 100%
Odds pick hit ✓

The odds pick is simply the betting-line favorite; the crowd pick is how PickemSZN users are picking — not a proprietary model. See all Week 12 picks & predictions →

Betting lines

Moneyline
Buffalo Bills: 1.41
New Orleans Saints: 3.35
Spread
Buffalo Bills:
New Orleans Saints:
Over / Under

Odds are decimal (from Betfair) and reflect the market as of the last update. How to read these →

See the most popular picks for Week 12 →

Team stats

BUF NO
21 1st Downs 12
361 Total Yards 190
248 Passing 146
113 Rushing 44
8-13 3rd down efficiency 5-14
4-35 Penalties 4-24
2 Turnovers 1
34:38 Possession 25:22

Leaders

BUF

  • Passing Yards
    Josh Allen (QB) — 23/28, 260 YDS, 4 TD, 2 INT
  • Rushing Yards
    Devin Singletary (RB) — 15 CAR, 44 YDS
  • Receiving Yards
    Stefon Diggs (WR) — 7 REC, 74 YDS, 1 TD

NO

  • Passing Yards
    Trevor Siemian (QB) — 17/29, 163 YDS, 1 TD, 1 INT
  • Rushing Yards
    Tony Jones Jr. (RB) — 16 CAR, 27 YDS
  • Receiving Yards
    Lil'Jordan Humphrey (WR) — 3 REC, 47 YDS

Scoring summary

  • Q1 7:09 BUF Dawson Knox 7 Yd pass from Josh Allen (Tyler Bass Kick) 7–0
  • Q2 8:46 BUF Tyler Bass 34 Yd Field Goal 10–0
  • Q3 8:48 BUF Stefon Diggs 5 Yd pass from Josh Allen (Tyler Bass Kick) 17–0
  • Q3 4:19 BUF Dawson Knox 24 Yd pass from Josh Allen (Tyler Bass Kick) 24–0
  • Q4 14:54 NO Nick Vannett 11 Yd pass from Trevor Siemian (Two-Point Pass Conversion Failed) 24–6
  • Q4 8:17 BUF Matt Breida 23 Yd pass from Josh Allen (Tyler Bass Kick) 31–6

Standings

2025 AFC East Standings

TeamW-LPFPA
New England14-3490320
Buffalo12-5481365
Miami7-10347424
New York3-14300503

2025 NFC South Standings

TeamW-LPFPA
Carolina8-9311380
Tampa Bay8-9380411
Atlanta8-9353401
New Orleans6-11306383

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