Week 12 · 2025 NFL Season
Buffalo Bills vs Houston Texans
Thu, Nov 20, 2025, 8:15 PM EST · Prime Video
NRG Stadium, Houston
Final — Houston Texans win
Buffalo Bills visit the Houston Texans at NRG Stadium in Week 12 of the 2025 NFL season. Final: Buffalo Bills 19, Houston Texans 23.
Betting lines
Moneyline
Buffalo Bills: 1.34
Houston Texans: 3.35
Spread
Buffalo Bills: -6
Houston Texans: +6
Over / Under
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Odds are decimal (from Betfair) and reflect the market as of the last update. How to read these →
Injury report
Buffalo Bills
- Dorian Strong (CB) — Out
- Cole Bishop (S) — Questionable
- Dorian Williams (LB) — Questionable
- Ben VanSumeren (FB) — Questionable
- Tyler Bass (PK) — Questionable
Houston Texans
- Tank Dell (WR) — Questionable
- Layne Pryor (TE) — Questionable
- Logan Hall (DE) — Questionable
- Marlin Klein (TE) — Questionable
- Brevin Jordan (TE) — Questionable
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