Week 6 · 2025 NFL Season
Arizona Cardinals vs Indianapolis Colts
Sun, Oct 12, 2025, 1:00 PM EDT · FOX
Lucas Oil Stadium, Indianapolis
Final — Indianapolis Colts win
Arizona Cardinals visit the Indianapolis Colts at Lucas Oil Stadium in Week 6 of the 2025 NFL season. Final: Arizona Cardinals 27, Indianapolis Colts 31.
Betting lines
Moneyline
Arizona Cardinals: 1.80
Indianapolis Colts: 2.05
Spread
Arizona Cardinals: -1.5
Indianapolis Colts: +1.5
Over / Under
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Odds are decimal (from Betfair) and reflect the market as of the last update. How to read these →
Injury report
Arizona Cardinals
- Kaleb Proctor (DT) — Questionable
- Tip Reiman (TE) — Questionable
- Karson Sharar (LB) — Questionable
- Walter Nolen III (DT) — Questionable
- Garrett Williams (CB) — Questionable
Indianapolis Colts
- Spencer Shrader (PK) — Questionable
- Daniel Jones (QB) — Questionable
- Alec Pierce (WR) — Questionable
- Charvarius Ward (CB) — Questionable
- Hunter Wohler (S) — Questionable
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